تحميل كتاب Clinical Applications of Capillary Electrophoresis PDF
نبذة عن كتاب Clinical Applications of Capillary Electrophoresis
كتاب Clinical Applications of Capillary Electrophoresis
1999م - 1443هـ نبذه عن الكتاب: Clinical Applications of Capillary Electrophoresis Margaret A. Jenkins 1. Introduction Capillary electrophoresis (CE) is a new and innovative technique that separates charged or uncharged molecules in a thin buffer-filled capillary by the application of a very high voltage. Separations by CE are extremely fast: Some are achieved in less than 5 min, with reproducibility studies often showing coefficient of variation (CVs) of <2%. The outstanding characteristic of CE is that it is an extremely sensitive technique. Early workers reported separations greater than 1 million theoretical plates per meter by CE, which is 10× the sensitivity of high-performance liquid chromatography (HPLC). The development of automated sample injection has meant that CE can be integrated into a clinical setting in which turnaround of accurate, cost-effective results are paramount. Since 1937, when the original paper on electrophoresis by Tiselius was published (1), many scientific papers have documented the progress of CE. Hjerten (2) originally suggested the usefulness of CE for zone electrophoresis and isoelectric focusing. Some excellent reviews on CE have already been published. Gordon (3) covered construction of instrumentation used in CE, as has Deyl (4). Kuhr published a review of operational parameters and applications (5). Mazzeo and Krull (6) reviewed coated capillaries for both capillary zone electrophoresis and capillary isoelectric focusing. In 1992, Shihabi (7) reviewed clinical applications of CE. Later, Jenkins et al. (8) and Lehmann et al. (9) also reviewed capillary electrophoresis applications in clinical chemistry. .هذا الكتاب من تأليف غير معروف و حقوق الكتاب محفوظة لصاحبها
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